季報
季度報告
10-Q
2026-05-15
財政季度:2026年第一季度(截至2026年3月31日)
AI 繁中摘要
📄 申報類型:10-Q(季度報告)
🏢 公司:Cocrystal Pharma, Inc.(股票代碼:COCP)
📆 財政季度:2026年第一季度(截至2026年3月31日)
Cocrystal Pharma 公佈2026年第一季度業績,期內淨虧損約230萬美元(每股0.17美元),與去年同期淨虧損230萬美元(每股0.23美元)大致持平。季內錄得22.5萬美元政府補助收入(SBIR Phase I獎助金),但營運開支增至258萬美元(去年同期234萬美元),主要由於法律及顧問費用增加。
截至2026年3月31日,公司持有現金及受限制現金約476萬美元(2025年底:710萬美元)。期內經營活動現金流出約234萬美元。管理層明確指出,現有資金不足以支持未來12個月營運,對持續經營能力存在重大疑問,需依賴額外融資。💸
研發進展方面:
- 抗諾如病毒/冠狀病毒候選藥物CDI-988已獲FDA快速審批資格(Fast Track),並於2026年2月在Emory大學啟動1b期人類挑戰研究,首批受試者已於3月入組。🔬
- 流感項目:口服CC-42344的2a期挑戰研究因感染率偏低影響數據分析,公司正與英國CRO就退款或重做研究進行仲裁。同時,公司獲NIH/NIAID 50萬美元SBIR Phase I資助,研發新型口服廣譜抗流感候選藥物。🦠
- 丙肝項目CC-31244仍在尋求合作夥伴推進後期開發。
管理層展望:公司將繼續專注於抗病毒藥物研發,但短期內需解決資金問題。通脹及美國關稅政策可能進一步增加營運成本。若未能及時獲得資金,可能需要延遲、縮減或終止部分臨床試驗或研發項目。⚠️
投資者影響:公司正處於現金消耗階段,未來融資進度及臨床數據(尤其CDI-988挑戰研究結果)將是關鍵催化劑。與CRO的仲裁結果及流感項目進展亦值得關注。📉
展開英文正文
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10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2026 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number: 001-38418 COCRYSTAL PHARMA, INC. (Exact name of registrant as specified in its charter) Delaware 35-2528215 (State or Other Jurisdiction of (I.R.S. Employer Incorporation or Organization) Identification No.) 19805 North Creek Parkway Bothell, WA 98011 (Address of Principal Executive Office) (Zip Code) Registrant’s telephone number, including area code: 877-262-7123 Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐ Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). Yes ☒ No ☐ Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act. (Check one): Large accelerated filer ☐ Accelerated filer ☐ Non-accelerated filer ☒ Smaller reporting company ☒ Emerging growth company ☐ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐ Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act). Yes ☐ No ☒ Securities registered pursuant to Section 12(b) of the Act: Title of Each Class Trading Symbol(s) Name of each exchange on which registered Common Stock COCP The Nasdaq Stock Market LLC (The Nasdaq Capital Market) As of May 15, 2026, the number of outstanding shares of the registrant’s common stock, par value $0.001 per share, was approximately 13,787,453. COCRYSTAL PHARMA, INC. FORM 10-Q FOR THE QUARTER ENDED MARCH 31, 2026 INDEX Part I - FINANCIAL INFORMATION Item 1. Condensed Consolidated Balance Sheets F-1 Condensed Consolidated Statements of Operations F-2 Condensed Consolidated Statements of Stockholders’ Equity F-3 Condensed Consolidated Statements of Cash Flows F-4 Notes to the Condensed Consolidated Financial Statements F-5 Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations 3 Item 3. Quantitative and Qualitative Disclosures About Market Risk 10 Item 4. Controls and Procedures 10 Part II - OTHER INFORMATION Item 1. Legal Proceedings 11 Item 1. A. Risk Factors 11 Item 2. Unregistered Sales of Equity Securities and Use of Proceeds 11 Item 3. Defaults Upon Senior Securities 11 Item 4. Mine Safety Disclosures 11 Item 5. Other Information 11 Item 6. Exhibits 12 SIGNATURES 13 2 Part I – FINANCIAL INFORMATION COCRYSTAL PHARMA, INC. CONDENSED CONSOLIDATED BALANCE SHEETS (in thousands, except per share data) March 31, 2026 December 31, 2025 (unaudited) Assets Current assets: Cash $4,685 $7,025 Restricted cash 75 75 Grant receivable 70 - Tax credit receivable 691 706 Prepaid expenses and other current assets 418 328 Total current assets 5,939 8,134 Property and equipment, net 81 93 Deposits 95 95 Operating lease right-of-use assets, net (including $89 and $152 to related party) 1,311 1,390 Total assets $7,426 $9,712 Liabilities and stockholders’ equity Current liabilities: Accounts payable and accrued expenses $1,886 $1,876 Current maturities of operating lease liabilities (including $58 and $49 to related party) 343 334 Total current liabilities 2,229 2,210 Long-term liabilities: Operating lease liabilities (including $32 and $104 to related party) 1,081 1,171 Total long-term liabilities 1,081 1,171 Total liabilities 3,310 3,381 Commitments and contingencies - - Stockholders’ equity: Common stock, $0.001 a par value: 100,000 shares authorized as of March 31, 2026 and December 31, 2025; 13,787 and 13,784 shares issued and outstanding as of March 31, 2026 and December 31, 2025 13 13 Additional paid-in capital 348,651 348,567 Accumulated deficit (344,548) (342,249) Total stockholders’ equity 4,116 6,331 Total liabilities and stockholders’ equity $7,426 $9,712 See accompanying notes to condensed consolidated financial statements. F-1 COCRYSTAL PHARMA, INC. CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (unaudited) (in thousands, except per share data) 2026 2025 Three months ended March 31, 2026 2025 Revenues and grant income: Grant income 225 - Operating expenses: Research and development 1,371 1,360 General and administrative 1,210 981 Total operating expenses 2,581 2,341 Loss from operations (2,356) (2,341) Other income: Interest income, net 22 37 Foreign exchange gain, net 35 3 Total other income, net 57 40 Net loss $(2,299) $(2,301) Net loss per common share, basic and diluted $(0.17) $(0.23) Weighted average number of common shares, basic and diluted 13,786 10,174 See accompanying notes to condensed consolidated financial statements. F-2 COCRYSTAL PHARMA, INC. CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY For the three months ended March 31, 2026 and 2025 (unaudited) (in thousands) Shares Amount Capital Deficit Equity Common Stock Additional Paid-in Accumulated Total Stockholders’ Shares Amount Capital Deficit Equity Balance as of December 31, 2025 13,784 $13 $348,567 $(342,249) $ 6,331 Stock-based compensation - - 84 84 Shares issued from RSU Award 3 - - - - Net loss - - - (2,299) (2,299) Balance as of March 31, 2026 13,787 $13 $348,651 $(344,548) $4,116 Common Stock Additional Paid-in Accumulated Total Stockholders’ Shares Amount Capital Deficit Equity Balance as of December 31, 2024 10,174 $10 $342,931 $(333,418) $ 9,523 Balance 10,174 $10 $342,931 $(333,418) $ 9,523 Stock-based compensation - - 82 - 82 Net loss - - - (2,301) (2,301) Balance as of March 31, 2025 10,174 $10 $343,013 $(335,719) $7,304 Balance 10,174 $10 $343,013 $(335,719) $7,304 See accompanying notes to condensed consolidated financial statements. F-3 COCRYSTAL PHARMA, INC. CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (unaudited) (in thousands) 2026 2025 Three months ended March 31, 2026 2025 Operating activities: Net loss $(2,299) $(2,301) Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization expense 12 25 Stock-based compensation 84 82 Decrease right of use assets 79 74 Changes in operating assets and liabilities: Grant receivable (70) - Prepaid expenses and other current assets (90) 45 Tax credit receivable 15 (229) Deposits - (57) Accounts payable and accrued expenses 10 (505) Operating lease liabilities (81) (73) Net cash used in operating activities (2,340) (2,939) Net decrease in cash and restricted cash (2,340) (2,939) Cash and restricted cash at beginning of period 7,100 9,935 Cash and restricted cash at end of period $4,760 $6,996 See accompanying notes to condensed consolidated financial statements. F-4 COCRYSTAL PHARMA, INC. NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS FOR THE THREE MONTHS ENDED MARCH 31, 2026 AND 2025 (unaudited) 1. Organization and Business Cocrystal Pharma, Inc. (“we”, the “Company” or “Cocrystal”), a clinical stage biopharmaceutical company incorporated in Delaware, has been developing novel technologies and approaches to create first-in-class or best-in-class antiviral drug candidates. Our focus is to pursue the development and commercialization of broad-spectrum antiviral drug candidates that will transform the treatment and prophylaxis of viral diseases in humans. By concentrating our research and development efforts on viral replication inhibitors, we plan to leverage our infrastructure and expertise in these areas. The Company’s activities since inception have principally consisted of acquiring product and technology rights, raising capital, and performing research and development. Successful completion of the Company’s development programs, obtaining regulatory approvals of its products and, ultimately, the attainment of profitable operations is dependent on future events, including, among other things, its ability to access potential markets, secure financing, develop a customer base, attract, retain and motivate qualified personnel, and develop strategic alliances. Liquidity and going concern The Company’s consolidated financial statements are prepared using generally accepted accounting principles in the United States of America applicable to a going concern, which contemplates the realization of assets and the satisfaction of liabilities in the normal course of business. The Company has incurred net losses and negative operating cash flows since inception. For the three months ended March 31, 2026, the Company recorded a net loss of approximately $2,299,000 and used approximately $2,340,000 of cash in operating activities. These factors raise substantial doubt about the Company’s ability to continue as a going concern. In addition, the Company’s independent registered public accounting firm, in its report on the Company’s December 31, 2025 financial statements, has expressed substantial doubt about the Company’s ability to continue as a going concern. The ability of the Company to continue as a going concern is dependent upon the Company’s ability to raise additional funds and implement its strategies. The financial statements do not include any adjustments that might be necessary if the Company is unable to continue as a going concern. On March 31, 2026, the Company had cash and restricted cash of approximately $4,760,000. Restricted cash represents amounts pledged as collateral for financing arrangements that are currently limited to the issuance of business credit cards. The restriction will end upon the conclusion of these financing arrangements. We believe that our current resources will not be sufficient to fund our operations beyond the next 12 months. This estimate is based, in part, upon our currently projected expenditures. The Company’s activities since inception have principally consisted of acquiring product and technology rights, raising capital, and performing research and development. Successful completion of the Company’s development programs, obtaining regulatory approvals of its products and, ultimately, the attainment of profitable operations is dependent on future events, including, among other things, its ability to develop, obtain approval and commercialize antiviral drug candidates, including access potential markets, secure financing, develop a customer base, and to attract, retain and motivate qualified personnel, and develop strategic alliances. Through March 31, 2026, the Company has primarily funded its operations through equity offerings and limited revenue. F-5 The Company will need to continue obtaining adequate capital to fund operating losses until it becomes profitable. The Company can give no assurances that the additional capital it is able to raise, if any, will be sufficient to meet its needs, or that any such financing will be obtainable on acceptable terms. Our future cash requirements, and the timing of those requirements, will depend on a number of factors, including economic conditions, the approval and success of our products in development, the continued progress of research and development of our product candidates, the timing and outcome of clinical trials and regulatory approvals, the costs involved in preparing, filing, prosecuting, maintaining, defending, and enforcing patent claims and other intellectual property rights, the status of competitive products, the availability of financing, our success in developing markets for our product candidates and legal proceedings that may arise. We have historically not generated sustained positive cash flow and if we are not able to secure additional funding when needed, we may have to delay, reduce the scope of, or eliminate one or more of our clinical trials or research and development programs. If the Company is unable to obtain adequate capital, it could be forced to cease operations or substantially curtail its drug development activities. The Company expects to continue incurring substantial operating losses and negative cash flows from operations over the next several years during its pre-clinical and clinical development phases. 2. Basis of Presentation and Significant Accounting Policies Basis of Presentation The accompanying condensed consolidated financial statements have been prepared in accordance with United States generally accepted accounting principles (“U.S. GAAP”) for interim financial information, the instructions to Form 10-Q and Article 10 of Regulation S-X set forth by the Securities and Exchange Commission (“SEC”). They do not include all of the information and notes required by U.S. GAAP for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring accruals) considered necessary for a fair presentation have been included. The results of operations for the interim periods presented are unaudited and are not necessarily indicative of the results of operations for the entire fiscal year. For further information, refer to the consolidated financial statements and footnotes thereto included in the Company’s annual report on Form 10-K for the year ended December 31, 2025 filed on March 31, 2026 (“Annual Report”). Principles of Consolidation The consolidated financial statements include the accounts of Cocrystal Pharma, Inc. and its wholly owned subsidiaries: Cocrystal Discovery, Inc., Cocrystal Pharma Australia Pty Ltd. (“Cocrystal Australia”), RFS Pharma, LLC and Cocrystal Merger Sub, Inc. Intercompany transactions and balances have been eliminated. Cocrystal Discovery, Inc. conducts all of the Company’s research and development activities and oversees ongoing clinical trials conducted by others. Cocrystal Australia operates clinical trials in Australia. The other two subsidiaries are inactive. Segments The Company’s Co-Chief Executive Officer and President (“CEO”) is our chief operating decision maker (“CODM”) and evaluates performance and makes operating decisions about allocating resources based on financial data presented on a consolidated basis. Because our CODM evaluates financial performance on a consolidated basis, the Company has determined that it operates as a single reportable segment composed of the consolidated financial results of Cocrystal Pharma, Inc. The measure of segment assets is reported on the consolidated balance sheets as total assets (see Note 9). F-6 Use of Estimates Preparation of the Company’s consolidated financial statements in conformance with U.S. GAAP requires the Company’s management to make estimates and assumptions that impact the reported amounts of assets, liabilities, revenues and expenses, and the disclosure of contingent assets and liabilities in the Company’s consolidated financial statements and accompanying notes. The most significant estimates in the Company’s consolidated financial statements relate to clinical trial costs and accruals and the fair value of stock-based compensation. The Company bases estimates and assumptions on historical experience, when available, and on various factors that it believes to be reasonable under the circumstances. The Company evaluates its estimates and assumptions on an ongoing basis, and its actual results may differ from estimates made under different assumptions or conditions. Concentrations of Credit Risk Financial instruments that potentially subject the Company to significant concentrations of credit risk consist primarily of cash deposited in accounts held at two U.S. financial institutions, which may, at times, exceed federally insured limits of $250,000 for each institution where accounts are held. At March 31, 2026 and December 31, 2025, our primary operating accounts held approximately $4,685,000 and $7,025,000, respectively, and our collateral account balance was $75,000 during both periods and held at a different institution. The Company has not experienced any losses in such accounts and believes it is not exposed to significant risks thereof. Risks and uncertainties The Company’s future results of operations involve a number of risks and uncertainties. Factors that could affect the Company’s future operating results and cause actual results to vary materially from expectations include, but are not limited to, rapid technological change, ability to obtain regulatory approvals, competition from currently available treatments and therapies, competition from larger companies, effective protection of proprietary technology, maintenance of strategic relationships, and dependence on key individuals. Products developed by the Company will require clearances from the U.S. Food and Drug Administration (the “FDA”) and other international regulatory agencies prior to commercial sales in their respective markets. The Company’s products may not receive the necessary clearances and if they are denied clearance, clearance is delayed, or the Company is unable to maintain clearance, the Company’s business could be materially, adversely impacted. See Item 1A- Risk Factors in our Annual Report on Form 10-K for the year ended December 31, 2025 for more information on the risks and uncertainties we face. Foreign Currency Transactions The Company and its subsidiaries use the U.S. dollar as functional currency. Foreign currency transactions are initially measured and recorded in the functional currency using the exchange rate on the date of the transaction. Foreign exchange gains and losses arising from settlement of foreign currency transactions are recognized in profit and loss. Cocrystal Australia maintains its records in Australian dollars. The monetary assets and liabilities of Cocrystal Australia are remeasured into the functional currency using the closing rate at the end of every reporting period. All nonmonetary assets and liabilities and related profit and loss accounts are remeasured into the functional currency using the historical exchange rates. Profit and loss accounts, other than those that are remeasured using the historical exchange rates, are remeasured into the functional currency using the average exchange rate for the period. Foreign exchange gains and losses arising from the remeasurement into the functional currency is recognized in profit and loss. Fair Value Measurements FASB Accounting Standards Codification (“ASC”) 820 defines fair value, establishes a framework for measuring fair value under U.S. GAAP and enhances disclosures about fair value measurements. Fair value is defined under ASC 820 as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value under ASC 820 must maximize the use of observable inputs and minimize the use of unobservable inputs. The standard describes a fair value hierarchy based on three levels of inputs, of which the first two are considered observable and the last unobservable, that may be used to measure fair value which are the following: Level 1 — quoted prices in active markets for identical assets or liabilities. F-7 Level 2 — other significant observable inputs for the assets or liabilities through corroboration with market data at the measurement date. Level 3 — significant unobservable inputs that reflect management’s best estimate of what market participants would use to price the assets or liabilities at the measurement date. At March 31, 2026 and December 31, 2025, the carrying amounts of financial assets and liabilities, such as cash, grant receivable, tax receivable, other assets, and accounts payable and accrued expenses approximate their fair values due to their short-term nature. The carrying values of leases payable approximate their fair values due to the fact that the interest rates on these obligations are based on prevailing market interest rates. Long-Lived Assets The Company regularly reviews the carrying value and estimated lives of its long-lived assets, including property and equipment, to determine whether indicators of impairment may exist which warrant adjustments to carrying values or estimated useful lives. The determinants used for this evaluation include management’s estimate of the asset’s ability to generate positive income from operations and positive cash flow in future periods as well as the strategic significance of the assets to the Company’s business objective. Should an impairment exist, the impairment loss would be measured based on the excess of the carrying amount over the asset’s fair value. Research and Development Expenses Research and development costs consist primarily of fees paid to consultants and outside service providers, and other expenses relating to the acquisition, design, development and testing of the Company’s clinical products. All research and development costs are expensed as incurred. Research and development costs are presented net of tax credits. The Company’s Australian subsidiary is entitled to receive government assistance in the form of refundable and non-refundable research and development tax credits (“Refundable Tax Credits”) from the federal and provincial taxation authorities, based on qualifying expenditures incurred during the fiscal year. The Refundable Tax Credits are from the provincial taxation authorities and are not dependent on its ongoing tax status or tax position and accordingly are not considered part of income taxes. The Company records Refundable Tax Credits as a reduction of research and development expenses when the Company can reasonably estimate the amounts and it is more likely than not, they will be received. As of March 31, 2026, the balance of Refundable Tax Credits was approximately $691,000. Income Taxes The Company accounts for income taxes under the asset and liability method. Under this method, deferred tax assets and liabilities are determined based on differences between financial reporting and tax bases of assets and liabilities and are measured using enacted tax rates and laws that are expected to be in effect when the differences are expected to be recovered or settled. Realization of deferred tax assets is dependent upon future taxable income. A valuation allowance is recognized if it is more likely than not that some portion or all of a deferred tax asset will not be realized based on the weight of available evidence, including expected future earnings. The Company recognizes an uncertain tax position in its financial statements when it concludes that a tax position is more likely than not to be sustained upon examination based solely on its technical merits. Only after a tax position passes the first step of recognition will measurement be required. Under the measurement step, the tax benefit is measured as the largest amount of benefit that is more likely than not to be realized upon effective settlement. This is determined on a cumulative probability basis. The full impact of any change in recognition or measurement is reflected in the period in which such change occurs. The Company elects to accrue any interest or penalties related to income taxes as part of its income tax expense. F-8 As of March 31, 2026, the Company assessed its income tax expense based on its projected future taxable income for the year ending December 31, 2025 and therefore recorded no amount for income tax expense for the three months ended March 31, 2026. In addition, the Company has significant deferred tax assets available to offset income tax expense due to net operating loss carry forwards which are currently subject to a full valuation allowance based on the Company’s assessment of future taxable income. Refer to our Annual Report on Form 10-K for the year ended December 31, 2025 for more information. Stock-Based Compensation The Company recognizes compensation expense using a fair value-based method for costs related to stock-based payments, including stock options. The fair value of options awarded to employees is measured on the date of grant using the Black-Scholes option pricing model and is recognized as expense over the requisite service period on a straight-line basis. Recognition of compensation expense for non-employees is in the same period and manner as if the Company had paid cash for the services. Use of the Black-Scholes option pricing model requires the input of subjective assumptions including expected volatility, expected term, and a risk-free interest rate. The Company estimates volatility using a blend of its own historical stock price volatility as well as that of market comparable entities since the Company’s common stock has limited trading history and limited observable volatility of its own. The expected term of the options is estimated by using the SEC Staff Bulletin No. 107’s Simplified Method for Estimate Expected Term. The risk-free interest rate is estimated using comparable published federal funds rates. Grant Income The Company accounts for government grant funding by analogy to ASC 958-605 because U.S. GAAP does not contain specific guidance for business entities receiving government grants. Grant income is recognized as the Company incurs qualifying research and development expenditures and satisfies the conditions associated with the grant arrangement. In October 2025, the Company announced that it had received a $500,000 Small Business Innovation Research (“SBIR”) Phase I award (the “Award”) from the National Institutes of Health (“NIH”) and the National Institute of Allergy and Infectious Diseases (“NIAID”). The Award supports the Company’s development of a novel oral broad-spectrum antiviral candidate for the treatment of influenza A and B infections. The Award is subject to the terms and provisions of Contract No. 75N93025C00038 entered into with NIAID, covering a performance period from September 2025 through September 2026. During the three months ended March 31, 2026, the Company recognized grant income of $225,000 under the Award related to qualifying expenditures incurred during the period. Of the total grant income recognized, $70,000 remained outstanding as of March 31, 2026 and was recorded as a grant receivable in the accompanying balance sheet. The grant receivable was subsequently collected in April 2026. Net Income (Loss) per Share The Company accounts for and discloses net income (loss) per common share in accordance with FASB ASC Topic 260, Earnings Per Share. Basic income (loss) per common share is computed by dividing income (loss) attributable to common stockholders by the weighted average number of common shares outstanding. Diluted net income (loss) per common share is computed by dividing net income (loss) attributable to common stockholders by the weighted average number of common shares that would have been outstanding during the period assuming the issuance of common stock for all potential dilutive common shares outstanding. Potential common shares consist of shares issuable upon the exercise of stock options and restricted stock units. The following table sets forth the number of potential common shares excluded from the calculations of net loss per diluted share because their inclusion would be anti-dilutive (in thousands): Schedule of Anti-dilutive Securities Excluded from Calculations of Net Loss Per Share 2026 2025 March 31, 2026 2025 Outstanding options to purchase common stock 838 549 Warrants to purchase common stock 7,223 - Unvested restricted stock units 77 155 Total 8,138 704 Recent Accounting Pronouncements In November 2024, the Financial Accounting Standards Board (FASB) issued ASU No. 2024-03, Income Statement—Reporting Comprehensive Income—Expense Disaggregation Disclosures (Subtopic 220-40): Disaggregation of Income Statement Expenses which includes amendments that require disclosure in the notes to financial statements of specified information about certain costs and expenses, including purchases of inventory; employee compensation; and depreciation, amortization and depletion expenses for each caption on the income statement where such expenses are included. The amendments are effective for the Company’s annual periods beginning January 1, 2027, with early adoption permitted, and should be applied either prospectively or retrospectively. The Company is in the process of evaluating this ASU to determine its impact on the Company’s disclosures. Other authoritative guidance issued by the FASB (including technical corrections to the ASC), the American Institute of Certified Public Accountants, and the SEC did not, or are not expected to, have a material impact on the Company’s consolidated financial statements and related disclosures. F-9 3. Property and Equipment Property and equipment are recorded at cost and depreciated over the estimated useful lives of the underlying assets (3three to five years) using the straight-line method. As of March 31, 2026, and December 31, 2025, property and equipment consist of (table in thousands): Schedule of Property and Equipment March 31, 2026 December 31, 2025 Lab equipment (excluding equipment under finance leases) $1,777 $1,777 Finance lease right-of-use lab equipment obtained in exchange for finance lease liabilities, net 162 162 Computer and office equipment 155 155 Total property and equipment 2,094 2,094 Less: accumulated depreciation and amortization (2,013) (2,001) Property and equipment, net $81 $93 Total depreciation and amortization expense were approximately $12,000 and $25,000 for the three months ended March 31, 2026 and 2025, For additional finance leases information, refer to Note 7 – Commitments and Contingencies. 4. Accounts Payable and Accrued Expenses Accounts payable and accrued expenses consisted of the following (in thousands) as of: Schedule of Accounts Payable and Accrued Expenses March 31, 2026 December 31, 2025 Accounts payable $1,371 $890 Accrued compensation 101 85 Accrued other expenses 414 901 Total accounts payable and accrued expenses $1,886 $1,876 Accounts payable and accrued expenses contain unpaid general and administrative expenses and costs related to research and development that have been billed and estimated unbilled, respectively, as of period-end. 5. Common Stock and Warrants As of March 31, 2026, the Company has authorized 100,000,000 shares of common stock, $0.001 par value per share. The Company had 13,787,000 and 13,784,000 shares issued and outstanding as of March 31, 2026 and December 31, 2025. The holders of common stock are entitled to one vote for each share of common stock held. On September 12, 2025, the Company, entered into a securities purchase agreement with certain accredited investors, pursuant to which the Company sold to the investors (i) in a registered direct offering, an aggregate of 2,764,710 shares of the Company’s common stock, at a price of $1.70 per share and (ii) in a concurrent private placement, warrants to purchase up to an aggregate of 5,529,420 shares of common stock (“the Investor Warrants”), at an initial exercise price of $1.50 per share. The Investor Warrants are exercisable upon issuance and will expire on September 27, 2027. Wainwright acted as the Company’s placement agent in connection with this offering. The Company paid Wainwright consideration consisting of (i) a cash fee equal to 7.0% of the aggregate gross proceeds in the offering, (ii) a management fee equal to 1.0% of the aggregate gross proceeds in the offering, (iii) reimbursement of certain expenses and (iv) warrants to acquire up to an aggregate of 207,353 shares of common stock (the “Placement Agent Warrants”). The Placement Agent Warrants are similar to the Investor Warrants, except that the initial exercise price of the Placement Agent Warrants is $2.125 per share. The Company received net proceeds of $4,183,000 from the sale of its common shares and warrants in the direct offering. Warrant Activity Table: Schedule of Warrants Activity Total Options Outstanding Weighted Average Exercise Price Aggregate Intrinsic Value Balance at December 31, 2025 7,222,821 $1.46 $ - Granted - - - Exercised - - - Forfeited - - - Outstanding at March 31, 2026 7,222,821 $1.46 $- 6. Stock Based Awards Equity Incentive Plans The Company adopted an equity incentive plan in 2015 (the “2015 Plan”) under which 833,333 shares of common stock have been reserved for issuance to employees, and non-employee directors and consultants of the Company. Recipients of incentive stock options granted under the 2015 Plan shall be eligible to purchase shares of the Company’s common stock at an exercise price equal to no less than the estimated fair market value of such stock on the date of grant. The maximum term of options granted under the 2015 Plan is ten years. On June 16, 2021, the Company’s stockholders voted to approve an amendment to the 2015 Plan to increase the number of shares of common stock authorized for issuance under the 2015 Plan from 416,667 to 833,333 shares. As of March 31, 2026, no shares remained available for future grants under the 2015 Plan. The 2015 Plan expired on June 29, 2025. F-10 On April 2, 2025, the Board of Directors of the Company approved and adopted an Equity Incentive Plan (the “2025 Plan”), which has an effective date of March 31, 2025. On June 25, 2025, the 2025 Plan was approved by our stockholders at our annual meeting of stockholders. The 2025 Plan provides for the grant of incentive stock options, qualified stock options, restricted stock awards, restricted stock units, stock appreciation rights, and performance shares or units and cash awards. Awards may be granted under the 2025 Plan to our employees, directors and independent contractors. the aggregate number of shares of Common Stock which shall be available for grants or payments of Awards under the 2025 Plan during its term shall initially be 1,500,000 (the “Total Plan Shares”). The Total Plan Shares will automatically increase on January 1st of each year, for a period of nine years commencing on January 1, 2026, in an amount equal to 5% of the total number of shares of Common Stock outstanding as of December 31 of the preceding calendar year on a fully diluted basis. The 2025 Plan also provides that, notwithstanding the annual increase provision, in no event will the increase in Total Plan Shares available under the 2025 Plan pursuant to the increase provision exceed 2,500,000 additional shares (or a total of up to 4,000,000 Total Plan Shares), subject to adjustment as provided under the 2025 Plan. As of March 31, 2026, 1,893,940 shares remained available for future grants under the 2025 Plan. Common Stock Reserved for Future Issuance The following table presents information concerning common stock available for future issuance (in thousands) as of March 31, 2026: Schedule of Common Stock Available for Future Issuance Shares Available for Grant Stock options issued and outstanding 838 Restricted stock units issued and outstanding 221 Shares authorized for future option grants 1,894 Warrants outstanding 7,223 Balance at March 31, 2026 $10,176 Total $10,176 Stock Options The following table summarizes stock option transactions for the 2015 and 2025 Plan, collectively, for the three months ended March 31, 2026 (in thousands, except per share amounts): Schedule of Stock Option Transactions Total Options Outstanding Weighted Average Exercise Price Aggregate Intrinsic Value Balance at December 31, 2025 537 $8.91 $ - Exercised - - - Granted 319 1.1 - Cancelled (18) 1.24 - Balance at March 31, 2026 838 $6.10 $- In January 2026, the Compensation Committee of the Company’s Board of Directors granted a total of 318,966 stock options with a fair value of $299,000 effective as of January 9, 2026. The Company granted stock options to directors, executives, employees, and consultants. The options are ten-year incentive stock options exercisable at $1.10 per share and vesting as follows: one-half vest on the one-year anniversary of the grant date and the remainder vest in eight equal quarterly instalments commencing on March 31, 2027. The fair value of share option award is estimated using the Black-Scholes option pricing method based on the following weighted-average assumptions: Schedule of Fair Value of Share Option Award Three months ended March 31, 2026 2025 Risk-Free interest rate 3.83% 0.00% Expected dividend yield 0.00% 0.00% Expected volatility 106.3 - Expected term (in years) 5.77 - Restricted Stock Units On August 12, 2024, the Company’s Compensation Committee approved the issuance of 256,000 restricted stock unit (“RSU”) awards to non-employee directors, officers, consultants and employees. The aggregate fair value of the restricted stock unit awards granted was estimated to be $451,000 using the market price of the stock on the date of the grant which is expensed using the straight-line method over the vesting period. Schedule of Restricted Stock Units Total Restricted Stock Units Outstanding Weighted Average Fair Value Aggregate Intrinsic Value Unvested December 31, 2025 97 $1.76 $ - Granted - - - Forfeited (6) - - Vested (15) - - Unvested and expected to vest at March 31, 2026 76 $1.76 $- F-11 The Company accounts for share-based awards to employees and nonemployee directors and consultants in accordance with the provisions of ASC 718, Compensation—Stock Compensation., and under the recently issued guidance following FASB’s pronouncement, ASU 2018-07, Compensation—Stock Compensation (Topic 718): Improvements to Nonemployee Share-Based Payment Accounting. Under ASC 718, and applicable updates adopted, share-based awards are valued at fair value on the date of grant and that fair value is recognized over the requisite service, or vesting, period. The Company values its equity awards using the Black-Scholes option pricing model, and accounts for forfeitures when they occur. For the three months ended March 31, 2026 and 2025, equity-based compensation expense recorded was approximately $84,000 and $82,000, respectively. As of March 31, 2026, there was approximately $279,000 of total unrecognized compensation expense related to non-vested stock options that is expected to be recognized over a weighted average period of 1.3 years. For options granted and outstanding, there were 838,351 options outstanding which were fully vested or expected to vest, with an aggregate intrinsic value of $ 0.00, a weighted average exercise price of $6.10 and weighted average remaining contractual term of 7.14 years at March 31, 2026. For vested and exercisable options, outstanding shares totaled 823,840, with an aggregate intrinsic value of $ 0.00. These options had a weighted average exercise price of $ 9.07 per share and a weighted-average remaining contractual term of 5.61 years at March 31, 2026. The aggregate intrinsic value of outstanding and exercisable options at March 31, 2026 was calculated based on the closing price of the Company’s common stock as reported on The Nasdaq Capital Market on March 31, 2026 of $1.01 per share less the exercise price of the options. The aggregate intrinsic value is calculated based on the positive difference between the closing fair market value of the Company’s common stock and the exercise price of the underlying options. 7. Commitments and Contingencies Commitm