重大事件
即時報告
8-K
2026-08-10
Annexon委任視網膜外科專家Blumenkranz入董事會 為地理萎縮療法商業化鋪路
AI 繁中摘要
申報類型:8-K(附展品99.1)
事件重點:Annexon, Inc.(納斯達克:ANNX)於2026年8月10日宣布,委任著名視網膜外科醫生及生物科技企業家 Mark S. Blumenkranz 醫生加入董事會。同時,擔任董事逾11年的 Muneer Satter 將卸任。
Blumenkranz 醫生擁有超過四十年臨床、科研及企業領導經驗,專注推動視網膜疾病的創新療法。他曾任史丹福大學眼科系主任及 Byers Eye Institute 創始總監,目前為史丹福大學眼科榮譽教授。他曾創辦或領導多家眼科及生命科學公司,包括 Adverum Biotechnologies、Optimedica(獲 Abbott Medical Optics 收購)、Oculeve(獲 Allergan 收購)及 Kedalion Therapeutics(獲 Novartis 收購),並曾擔任 Verana Health 的創辦人及董事。
管理層展望:行政總裁 Douglas Love 表示,Blumenkranz 的視網膜專業知識、生物科技領導經驗及建立成功公司的能力,將為公司推進 vonaprument 治療地理萎縮(geographic atrophy)及準備商業化提供重大戰略價值。Blumenkranz 則指出,Annexon 針對 C1q 的平台方法有望為地理萎縮患者提供真正保留視力的治療方案,並期待隨著 vonaprument 邁向第三期關鍵數據及潛在註冊而共同努力。
公司背景:Annexon 專注開發針對神經炎症疾病的下一代免疫療法,全球影響近1,000萬人。其科學基礎是靶向 C1q——經典補體路徑的啟動分子,旨在從源頭阻止補體驅動的神經炎症。
潛在影響:此高層人事變動反映公司正為後期臨床項目的關鍵數據及潛在商業化鋪路;Blumenkranz 的行業網絡及商業化經驗或有助提升投資者對其眼科管線的信心。Satter 卸任屬長期服務後的正常更替,暫未見負面信號。
展開英文正文
EX-99.1 2 d130710dex991.htm EX-99.1 EX-99.1 Exhibit 99.1 Annexon Appoints Renowned Retinal Surgeon and Biotechnology Entrepreneur Mark S. Blumenkranz, M.D., M.M.S. to its Board of Directors Over Four Decades of Clinical, Scientific and Corporate Leadership Advancing Innovation in Retinal Disease BRISBANE, Calif., August 10, 2026 – Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing the next generation platform of targeted immunotherapies for multiple neuroinflammatory diseases that impact nearly 10 million people worldwide, today announced the appointment of Mark S. Blumenkranz, M.D., M.M.S., to its board of directors. Dr. Blumenkranz, a renowned retinal surgeon and biotechnology entrepreneur, brings more than four decades of clinical, scientific and corporate leadership experience advancing innovative therapies for retinal disease. The Company also announced that Muneer Satter will step down from the board after more than 11 years of distinguished service and steadfast support as a director and investor. “We are delighted to welcome Mark to our board of directors as Annexon enters its next phase of growth, advancing two late-stage clinical programs with potential to help millions of patients worldwide,” said Douglas Love, president and chief executive officer of Annexon. “Mark’s unique combination of retinal expertise, biotechnology leadership, and experience building successful companies will provide tremendous strategic value as we advance vonaprument in geographic atrophy and prepare for commercialization. Mr. Love continued, “We are also deeply grateful to Muneer for his many years of service, strategic guidance and unwavering support since joining our Board in 2015. As a trusted advisor and investor with strong conviction in our platform, Muneer played an instrumental role in the company’s evolution from a preclinical stage organization into a public biotechnology company clinically advancing a robust late-stage pipeline for neuroinflammatory diseases. We thank Muneer for his many contributions and wish him continued success in his future endeavors.” Dr. Blumenkranz added, “Annexon’s C1q-targeted platform approach is uniquely positioned to help patients across a range of neuroinflammatory diseases and importantly, represents a differentiated path forward for patients with geographic atrophy, a disease that has lacked a truly vision-sparing treatment option. I look forward to working with the board and the management team as vonaprument advances toward pivotal Phase 3 data and potential registration.” Mark S. Blumenkranz, M.D., M.M.S., is the H.J. Smead Professor Emeritus of Ophthalmology at Stanford University School of Medicine and Co-Director of Stanford’s Ophthalmic Innovation Program. An internationally recognized retinal specialist, surgeon, entrepreneur and innovator, Dr. Blumenkranz previously served as Chair of Stanford’s Department of Ophthalmology and founding Director of the Byers Eye Institute at Stanford. Throughout his distinguished career, he has helped pioneer advances in retinal surgery, drug delivery, ophthalmic imaging and gene therapy, while authoring more than 175 peer-reviewed publications and holding numerous patents. He has co-founded and led numerous ophthalmic and life sciences companies through development, commercialization and successful acquisition, including Adverum Biotechnologies, where he served as co-founder and chairman of the board; Optimedica Corporation, which was acquired by Abbott Medical Optics; Oculeve, which was acquired by Allergan; and Kedalion Therapeutics, where he served as founding chairman and chief executive officer until its acquisition by Novartis. He was also a founder and director of Verana Health. Dr. Blumenkranz currently serves as Managing Director of Lagunita Biosciences and sits on the boards of several ophthalmic and life sciences companies. He received his undergraduate degree, master’s degree in biochemical pharmacology, and M.D. from Brown University, completed his ophthalmology residency at Stanford University, and a fellowship in vitreoretinal diseases at the Bascom Palmer Eye Institute. About Annexon Annexon Biosciences (Nasdaq: ANNX) is advancing the next generation platform of targeted immunotherapies for nearly 10 million people worldwide living with serious neuroinflammatory diseases. Our founding scientific approach focuses on C1q, the initiating molecule of a potent inflammatory pathway that when misdirected can lead to tissue damage and loss of function in a host of diseases. Our targeted therapies are designed to stop classical complement-driven neuroinflammation at its source to provide meaningful functional benefit and alter the course of disease. Annexon’s mission is to deliver game-changing therapies to patients so that they can live their best lives. To learn more visit annexonbio.com. Forward Looking Statements This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. In some cases, you can identify forward-looking statements by terminology such as “aim,” “anticipate,” “assume,” “believe,” “contemplate,” “continue,” “could,” “design,” “due,” “estimate,” “expect,” “goal,” “intend,” “may,” “objective,” “plan,” “positioned,” “potential,” “predict,” “seek,” “should,” “target,” “will,” “would” and other similar expressions that are predictions of or indicate future events and future trends, or the negative of these terms or other comparable terminology. All statements other than statements of historical facts contained in this press release are forward-looking statements. These forward-looking statements include, but are not limited to, statements about: the company’s ability to advance vonaprument in geographic atrophy and prepare for commercialization, if approved; the benefit of the company’s C1q-targeted platform and its ability to help patients across a range of neuroinflammatory diseases; and continuing advancement of the company’s portfolio. Forward-looking statements are not guarantees of future performance and are subject to risks and uncertainties that could cause actual results and events to differ materially from those anticipated, including, but not limited to, risks and uncertainties related to: the company’s history of net operating losses; the company’s ability to obtain necessary capital to fund its clinical programs; the early stages of clinical development of the company’s product candidates; the effects of public health crises on the company’s clinical programs and business operations; the company’s ability to obtain regulatory approval of and successfully commercialize its product candidates; any undesirable side effects or other properties of the company’s product candidates; the company’s reliance on third-party suppliers and manufacturers; the outcomes of any future collaboration agreements; and the company’s ability to adequately maintain intellectual property rights for its product candidates. These and other risks are described in greater detail under the section titled “Risk Factors” contained in the company’s Annual Report on Form 10-K and Quarterly Reports on Form 10-Q and the company’s other filings with the SEC. Any forward-looking statements that the company makes in this press release are made pursuant to the Private Securities Litigation Reform Act of 1995, as amended, and speak only as of the date of this press release. Except as required by law, the company undertakes no obligation to publicly update any forward-looking statements, whether as a result of new information, future events or otherwise. Investor Contact: Joyce Allaire LifeSci Advisors [email protected] Media Contact: Beth Keshishian 917-912-7195 [email protected]